Freund

This study evaluates the sustainability and performance advantages of a naturally sourced hydroxypropyl pea starch-based film coating system (ReadiLYCOAT® [RL], Roquette), compared to conventional film polymer coatings in pharmaceutical manufacturing. RL is compared to Tabshield® H semi-synthetic HPMC-based coating system (Roquette) and Tabshield® P synthetic PVA-based coating system (Roquette). The research investigates sustainability attributes and manufacturing performance, focusing on energy consumption during the coating process of temperature-sensitive drug products at product bed temperatures below 35°C, contrasted with HPMC- and PVA-based polymers requiring higher bed temperatures. Additionally, the study assesses the efficiency of equipment cleaning procedures. By quantifying these factors under industrial-scale conditions, this research provides a comprehensive evaluation of RL’s potential to enhance ecological and operational outcomes in pharmaceutical film coating applications.