Spray drying granulation in a fluid bed is a process that transforms liquid feeds (solutions, suspensions, or slurries) directly into free-flowing, coarse granules by spraying them into an empty fluidized […]
Key Highlights Granulation transforms fine powders into larger, uniform particles, improving flowability, compressibility, and reducing segregation and dust generation in pharmaceutical manufacturing. Dry granulation uses mechanical compression to form […]
With great sadness, we announce the passing of Yasutoyo (Yas) Fusejima, the founder of Freund Corporation, parent company of Freund Group. His vision and passion for innovation has left […]
How three critical processes are shaping the future of energy storage. In an era dominated by the quest for sustainable energy solutions, the significance of battery technology cannot be overstated. […]
Sustainability, customisation, and automation are key factors to remaining flexible in a continuously evolving pharma industry. Vice President of Global Business Development at Freund-Vector, Jamie Frizzell, joins Pharma Tech Talks […]
FREUND’s Technical Service Engineer for Brazil Renato Oliveira and Validation Engineer, Gavin Peterson successfully completed a 2 week trip for equipment validation at the Novamed site in Brazil. This machine […]
NIR spectroscopy provided significant advantages over offline moisture measurement in terms of time for sample analysis without a drop off in accuracy. In this study, repeatable moisture curves for a […]
Until now, batch manufacturing has been the main mode of pharmaceutical manufacture: raw materials are input and processed in a stage of the process then removed for input and process […]
Process Analytical Technology (PAT) is a system for designing, analyzing, and controlling pharmaceutical manufacturing processes through measurements of critical quality and performance attributes of raw and processed materials to ensure […]
The DVA Chemical Company and Freund-Vector joined forces on a study to expose a new water dispersible pharmaceutical coating product able to be applied at tablet bed process temperatures lower […]
Use Of Different Mannitol Grades To Improve The Flow And Tableting Properties Of Powder Mixtures Dry Granulated By Roller Compaction The Freund-Vector European Laboratories co-authored an important study presented at […]
The number of highly potent drugs in OSD (Oral Solid Dosage) production has risen sharply in recent years. As a result, containment is becoming ever more […]
Along with my staff here at the Freund-Vector European Laboratory, we are happy to help address your processing requirements and provide on-site and online training. After working in the industry […]
PRESS RELEASE FOR IMMEDIATE RELEASE: November 9, 2020 Notice of Acquisition of Cos.Mec of Italy On November 5, 2020, Freund Corporation, Tokyo Japan, acquired Cos.Mec S.r.l., a privately owned […]
The GRANUMEIST® (GMX) High Shear Granulator Mixer systems have been used for decades in the pharmaceutical industry. They are designed for efficient and homogeneous wet granulation of powders to form […]
As we endeavor to stem the spread of COVID-19, Freund-Vector has implemented a new service capability to ensure critical projects are not delayed. Freund-Vector has begun carrying out Factory Acceptance […]
Dear valued clients, global partners and supporters: As we continue to monitor the latest information regarding the global COVID-19 outbreak, we are taking additional measures to ensure the safety of […]
Detection of Moisture Using a NIR Filter Photometer on Dynamically Moving Particles in a Rotor Processor On November 4-5, 2019, Mitch Crawford, Associate Process Scientist, Freund-Vector presented a poster at […]
Evaluation of Different Mannitol Grades in Dry Granulation Process by Roller Compaction The Freund-Vector European Laboratories co-authored in an important study presented at the AAPS show November 4-5, 2019. Along […]
Cannabis-infused products and medical marijuana are at the forefront of an innovative and promising industry. Fueled by a growing consumer base and enthusiasm, the race is on to develop effective, […]
VHC-Multi Pan Mounting Method Cedar Rapids, IA: August 29, 2019, The US Patent office announced a pending patent for a pan mounting method. This new design on the VHC-Multi allows for […]
The 9th International Granulation Workshop took place in Lausanne, Switzerland on June 26-28, 2019. The granulation conference is the place to showcase the latest in agglomeration, granulation and particle technology […]
Really? How can that be? After all, isn’t Mount Rush solid as a rock! True, but even rock dissolves when exposed to water. It will dissolve very, very, slowly over […]
Rotor Technology has been used to process multiparticulate pharmaceutical materials for many years, it’s an ideal situation for processing small particles. It provides excellent mixing, flowability with concurrent tangential spraying. […]
With fluid bed systems, safety always must be considered as the highest priority. Due to static discharge, there always remains the risk of an explosive environment within the fluid bed […]
Think about when you put hot cocoa powder mix in a mug of hot water, how much of the powder floats on top of the surface? How quickly do you […]
There are many types of used laboratory and process equipment are available on the secondary market. Most of what would be needed for a complete solid-dosage operation. Knowing the process […]
For the longest time, pharmaceuticals have been produced using a method known as “batch manufacturing,” which involves a multi-step, lengthy process that uses large-scale equipment. In recent years however manufacturing […]
A customer contacted Freund-Vector asking for a requirement to coat tablets on a LDCS-Pro Hi Coater (150L batches) and needed contained loading, sampling and unloading of their tablets. The customer […]
On March 25-26, 2019, Freund-Vector through a joint partnership with Chemische Fabrik Budenheim KG, presented a poster at the 3rd European Pharma Congress in Bologna Italy on “Adjusting the Release […]
Wurster Spray PAT Monitoring by NIR: Calibration vs. PCA Trend Approach The 3rd European Pharma Congress was held in Bologna Italy, March 25-26, 2019. The European Conferences on Pharmaceutics is […]
The purpose of the experiment was to evaluate and compare the performances of different spray guns in various coating processes in a Freund-Vector VHC-5811 55 liter fully perforated coating pan. […]
Last week Freund-Vector created a short quiz on Fluid Bed Processors on LinkedIn. The purpose of this quiz was to test customer’s knowledge on Freund-Vector’s Fluid Bed technology and processing […]
The Freund Group seeks to expand its non-pharmaceutical product business and take on new challenges that enable it to contribute to improving the quality of health and life of people […]
The National Institute for Pharmaceutical Technology & Education (NIPTE) is a collaboration of academia, industry and other stakeholders using research, outreach and education to improve the way medicines are designed, […]
The focus of this symposium was around Enabling Technologies and Innovation within the pharmaceutical industry. During this one-day event, there were presentations on a range of topics around formulation development, […]
Last week, Freund-Vector conducted a pilot test to determine if tablets could be coated at 250 mL/minute/gun. After two days of testing on Freund-Vector’s VHC HI-COATER® 60 Coating System, the […]
Are you the one who is responsible for installation and startup at your organization? Are you being told that there cannot be any issues or delays? Wouldn’t it be nice […]
This week Freund-Vector and Grain Processing Corporation (GPC) received a patent related to microspheres using Freund-Vector’s Granurex (GXR), the most powerful pellet/powder processor available in the market place. Microspheres composed […]
In the April edition of Tablets and Capsules, Mr. Nick Slater, Freund-Vector’s Senior Process Development Scientist, discusses the qualitative relationships between key parameters when using a perforated pan film coater. […]
Starting with the development of the world’s first successful automated film coating machine in 1964, the Freund group has established itself as a global leader in tablet coating systems and […]
Freund-Vector’s Process Scientists conducted a study to determine what happens to particle size and shape when different binder activations are used with high-shear granulation processes. This study was done with […]
Is there a solution that could take an existing Wurster process and transfer it to a conical rotor to reduce the processing time and pieces of equipment required to complete […]
Active Pharmaceutical Ingredients (API) layering onto multi-particulate core materials has become an increasingly popular method of drug delivery in the pharmaceutical industry in recent years. The ability to control dosing, […]
Most solid dosage drugs are manufactured using “batch” technology, a process where the finished product has been made after many stops and starts in a series of steps. In comparison, […]
Taste masking of multi-particulate dosage forms has become widespread in the pharmaceutical industry, particularly with small particles used in orally disintegrating tablets (ODT) applications. The amount of coating required to […]
Roller compaction is a dry granulation process used in the pharmaceutical industry to create granules for manufacturing solid dosage forms such as tablets and capsules. During the roller compaction operation, […]
During the past 20 years there have been substantial improvements in the variety and quality of tablet coating materials (i.e. ease of preparation, aqueous controlled release, reduced viscosity/higher solids, etc.). […]
Freund-Vector and Dow Chemical conducted a study of spray coatings of ethylecllulose for controlled release on multi-particulate dosage forms. Long process times, need for organic solvent capabilities and particulate agglomeration […]
The purpose of this research was to compare two processes, an established Wurster coating process and a GRANUREX® process for producing 100-300 micron Omeprazole coated beads to determine if advantages […]
