Novel Enteric Coating of Multi-Particulates with Dry Powder Application of Glidant Utilizing a Modified Wurster Spray Gun System

Bottom Spray Wurster technology is commonly used in the pharmaceutical industry as a method for applying active and functional coatings, including enteric coatings, to multiparticulate substrates. Typically dilute solutions or suspensions of polymer mixed with appropriate glidant to reduce blocking during the drying of the polymer coat is applied via air atomizing spray guns. Having to dilute the solution can increase the application time needed for enteric protection.

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