Effect of Particle Size and Shape on the Coating Level Required for Taste Masking Multi-Particulates Utilizing Dry Powder Layering

Taste masking of multi-particulate dosage forms has become widespread in the pharmaceutical industry, particularly with small particles used in ODT applications. The amount of coating required to fully mask the API can be variable as the size and shape of the substrate changes. This study attempts to quantify the effect of size and shape on the coating
requirements to fully taste mask multi-particulates.

Download the PDF