Evaluation of Lab vs Pilot Scale High Shear Granulation for Extended Release Tablets Containing Carbopol 971P Polymer

To evaluate the aqueous granulation process for guaifenesin formulations containing mid or high levels of Carbopol® 971P NF polymer (10% or 20% w/w) and to determine the effect of processing equipment (lab- vs. pilot-scale) on the granule and tablet properties and on drug release.

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