The Value of Factory Acceptance Tests (FAT)
Are you the one who is responsible for installation and startup at your organization? Are you being told that there cannot be any issues or delays? Wouldn’t it be nice […]
Patent Issued – Process and Product Produced on Freund-Vector’s GXR
This week Freund-Vector and Grain Processing Corporation (GPC) received a patent related to microspheres using Freund-Vector’s Granurex (GXR), the most powerful pellet/powder processor available in the market place. Microspheres composed […]
Basic Batch Coater Operating Parameters and Setup
In the April edition of Tablets and Capsules, Mr. Nick Slater, Freund-Vector’s Senior Process Development Scientist, discusses the qualitative relationships between key parameters when using a perforated pan film coater. […]
Freund-Vector’s Perforated Coating Pans
Starting with the development of the world’s first successful automated film coating machine in 1964, the Freund group has established itself as a global leader in tablet coating systems and […]
High-Shear Granulation Processes: Comparison of Different Methods of Binder Addition on Particle Size and Shape
Freund-Vector’s Process Scientists conducted a study to determine what happens to particle size and shape when different binder activations are used with high-shear granulation processes. This study was done with […]
Creating Enteric Coated Omeprazole Pellets on a Conical Rotor
Is there a solution that could take an existing Wurster process and transfer it to a conical rotor to reduce the processing time and pieces of equipment required to complete […]
Utilization of Starch Micro-Spheres-Facilitate High API Loading in Particles Below 250 Microns
Active Pharmaceutical Ingredients (API) layering onto multi-particulate core materials has become an increasingly popular method of drug delivery in the pharmaceutical industry in recent years. The ability to control dosing, […]
Continuous Manufacturing: Alternative to Batch Processing
Most solid dosage drugs are manufactured using “batch” technology, a process where the finished product has been made after many stops and starts in a series of steps. In comparison, […]
Taste Masking Multi-Particulates Utilizing Dry Polymer Layering
Taste masking of multi-particulate dosage forms has become widespread in the pharmaceutical industry, particularly with small particles used in orally disintegrating tablets (ODT) applications. The amount of coating required to […]
An Evaluation of a One-Step vs. Multi-Step Milling Process for Roller Compacted Ribbon
Roller compaction is a dry granulation process used in the pharmaceutical industry to create granules for manufacturing solid dosage forms such as tablets and capsules. During the roller compaction operation, […]
How The AT Spray Gun Improves Film Coating Processes
During the past 20 years there have been substantial improvements in the variety and quality of tablet coating materials (i.e. ease of preparation, aqueous controlled release, reduced viscosity/higher solids, etc.). […]
Comparison of Wurster and Dry Powder Layering Processes- Controlled Release Coatings of Ethylcellulose on Drug Loaded Multiparticulates
Freund-Vector and Dow Chemical conducted a study of spray coatings of ethylecllulose for controlled release on multi-particulate dosage forms. Long process times, need for organic solvent capabilities and particulate agglomeration […]
Troubleshooting Film Coating Process Problems
With any process, there are potential problems that need to be taken into consideration. In troubleshooting those problems, your first step should be to ensure that there are no equipment maintenance […]
Troubleshooting Granulation Process Problems
With any process, there are potential problems that need to be taken into consideration. In troubleshooting those problems, your first step should be to ensure that there are no equipment maintenance […]
The Evolution of On-Dose Product Identification
Print-Inspect-Protect Many business needs can be satisfied by providing unique identification on tablets and capsules. But there is truly only one purpose: patient safety. Managing risk in the increasingly complex […]
Coating Mini-Tablets Using Perforated Coating Pans
Novel Process Provides New Drug Delivery Solutions Mini-tablets offer a unique drug delivery method, combining multiparticulate dosage forms with traditional tablet formulation. When filled into a gelatin capsule, mini-tablets can […]
Freund-Vector’s On-Site Services
The Value of Freund-Vector’s Field Engineers Freud-Vector’s On-Site Services is designed to assist customers in the start-up and commissioning of Freund-Vector’s supplied equipment. On-Site Services are available globally and consist […]
Augmented Reality in Pharmaceutical Equipment Manufacturing
What Would Augment Reality? After reading the article posted by Luke Wroblewski, #lukew, “What Would Augment Reality?”, I posed this question to the Freund-Vector team. Was there information that could […]
Powder Layering Active Pharmaceutical Ingredient (API) with GXR
Novel Processing Technique Using Granurex GRANUREX® is a one-pot patented conical rotor insert that will fit within a VFC FLO-COATER® fluid bed system. There are four (4) primary applications that […]
What happens in Freund-Vector’s Laboratories?
The Value of Freund-Vector’s Laboratory Support Services Freud-Vector’s USA and European laboratories feature state-of-the art processing equipment, ranging from laboratory size to pilot scale systems with automated process controls. This […]