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News

Home > News, Notes and Solutions

High-Shear Granulation Processes: Comparison of Different Methods of Binder Addition on Particle Size and Shape

Freund-Vector’s Process Scientists conducted a study to determine what happens to particle size and shape when different binder activations are used with high-shear granulation processes.  This study was done with […]

Tagged wet granulation

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Creating Enteric Coated Omeprazole Pellets on a Conical Rotor

Is there a solution that could take an existing Wurster process and transfer it to a conical rotor to reduce the processing time and pieces of equipment required to complete […]

Tagged Granurex (GXR)

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Utilization of Starch Micro-Spheres-Facilitate High API Loading in Particles Below 250 Microns

Active Pharmaceutical Ingredients (API) layering onto multi-particulate core materials has become an increasingly popular method of drug delivery in the pharmaceutical industry in recent years. The ability to control dosing, […]

Tagged Dry Powder Layering

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Continuous Manufacturing: Alternative to Batch Processing

Most solid dosage drugs are manufactured using “batch” technology, a process where the finished product has been made after many stops and starts in a series of steps. In comparison, […]

Tagged Granulation

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Taste Masking Multi-Particulates Utilizing Dry Polymer Layering

Taste masking of multi-particulate dosage forms has become widespread in the pharmaceutical industry, particularly with small particles used in orally disintegrating tablets (ODT) applications. The amount of coating required to […]

Tagged Dry Powder Layering

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An Evaluation of a One-Step vs. Multi-Step Milling Process for Roller Compacted Ribbon

Roller compaction is a dry granulation process used in the pharmaceutical industry to create granules for manufacturing solid dosage forms such as tablets and capsules. During the roller compaction operation, […]

Tagged dry granulation

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How The AT Spray Gun Improves Film Coating Processes

During the past 20 years there have been substantial improvements in the variety and quality of tablet coating materials (i.e. ease of preparation, aqueous controlled release, reduced viscosity/higher solids, etc.). […]

Tagged Film Coating

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Comparison of Wurster and Dry Powder Layering Processes- Controlled Release Coatings of Ethylcellulose on Drug Loaded Multiparticulates

Freund-Vector and Dow Chemical conducted a study of spray coatings of ethylecllulose for controlled release on multi-particulate dosage forms.  Long process times, need for organic solvent capabilities and particulate agglomeration […]

Tagged Granurex (GXR), Wurster Technology

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Comparison of Wurster processor with a GRANUREX® (GXR) rotor processor: 100-300 micron Omeprazole coated beads

The purpose of this research was to compare two processes, an established Wurster coating process and a GRANUREX® process for producing 100-300 micron Omeprazole coated beads to determine if advantages […]

Tagged Granurex (GXR), Wurster Technology

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Troubleshooting Film Coating Process Problems

With any process, there are potential problems that need to be taken into consideration. In troubleshooting those problems, your first step should be to ensure that there are no equipment maintenance […]

Tagged Film Coating

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Troubleshooting Granulation Process Problems

With any process, there are potential problems that need to be taken into consideration. In troubleshooting those problems, your first step should be to ensure that there are no equipment maintenance […]

Tagged Granulation, TFC Roll Compactor

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The Evolution of On-Dose Product Identification

Print-Inspect-Protect Many business needs can be satisfied by providing unique identification on tablets and capsules.  But there is truly only one purpose: patient safety.  Managing risk in the increasingly complex […]

Tagged On-Dose Printing, TABREX: Tablet Inspection and Printer

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Coating Mini-Tablets Using Perforated Coating Pans

Novel Process Provides New Drug Delivery Solutions Mini-tablets offer a unique drug delivery method, combining multiparticulate dosage forms with traditional tablet formulation.  When filled into a gelatin capsule, mini-tablets can […]

Tagged Coat, Hi-Coater: Tablet Coater

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Freund-Vector’s On-Site Services

The Value of Freund-Vector’s Field Engineers Freud-Vector’s On-Site Services is designed to assist customers in the start-up and commissioning of Freund-Vector’s supplied equipment.  On-Site Services are available globally and consist […]

Tagged On-Site Services

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Augmented Reality in Pharmaceutical Equipment Manufacturing

What Would Augment Reality? After reading the article posted by Luke Wroblewski, #lukew, “What Would Augment Reality?”, I posed this question to the Freund-Vector team.  Was there information that could […]

Tagged Augmented Reality

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Powder Layering Active Pharmaceutical Ingredient (API) with GXR

Novel Processing Technique Using Granurex GRANUREX® is a one-pot patented conical rotor insert that will fit within a VFC FLO-COATER® fluid bed system.  There are four (4) primary applications that […]

Tagged Granurex (GXR)

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Fastest Method to Powder Coat Pellets Using Dow’s Ethocel™HP

Granurex Technology Integral to Novel Processing Technique Freund-Vector’s GXR technology and Dow’s Ethocel™ HP allows customers to coat multiparticulates without the need for solvent or aqueous-based polymers.   This new technology […]

Tagged Ethocel HP, Granurex (GXR), Powder Coating

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What happens in Freund-Vector’s Laboratories?

The Value of Freund-Vector’s Laboratory Support Services Freud-Vector’s USA and European laboratories feature state-of-the art processing equipment, ranging from laboratory size to pilot scale systems with automated process controls.  This […]

Tagged FV: Italy Lab, FV: Marion Lab

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Scaling Roll Compaction

Freund-Vector offers solid solutions from feasibility to production Freund-Vector’s comprehensive line-up of roll compaction equipment is designed to assist customers with developing and manufacturing pharmaceutical products in the most efficient […]

Tagged TFC Roll Compactor, TFC-1230, TFC-220, TFC-LAB Micro

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Freund-Vector’s Granumeist High Shear Granulation Systems

Differences Between Top and Bottom Drive Processors Freund-Vector’s GRANUMEIST® High Shear Granulation system is designed for efficient and homogeneous wet granulation of powders to form medium to high density granules […]

Tagged Granumeist: High Shear Granulator

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  • Home
  • About
    • Overview
    • Mission Values
    • Map/Airport Directions
    • Careers
    • ISO 9001:15 Certified
  • Technologies
    • Fluid Bed: Top Spray Granulation
    • Fluid Bed: Wurster Coating
    • Fluid Bed: Wurster Powder Coating
    • Fluid Bed: GRANUREX® Granulation and Coating
    • Fluid Bed: Drying
    • Pan Coater: Tablet Coating
    • High Shear Granulator: Wet Granulation
    • Roller Compaction: Continuous Dry Granulation
    • Spray Drying
  • Products
    • Fluid Beds (FLO-COATERS®)
    • High Shear Mixers (GRANUMEIST®)
    • Roll Compaction (Granuforce™)
    • Tablet Coaters (HI-COATERS®)
    • Spray Dryers (Genesis™)
    • Powder Handling
    • COMPU™
  • Labs
    • USA Lab
    • European Lab
  • Sales and Service
    • Full Circle Service™
    • Find a Sales Representative
    • Request Information
    • Request for Training
    • Technical Support/Repair Parts
  • Knowledge Center
    • Posters
    • Case Studies and Whitepapers
    • News, Notes and Solutions
    • Upcoming Events
  • Project Management
  • Group Companies
    • Freund Corporation (English)
    • Freund-Turbo Corporation

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