Yasutoyo (Yas) Fusejima Has Passed Away at Age 87
With great sadness, we announce the passing of Yasutoyo (Yas) Fusejima, the founder of Freund Corporation, parent company of Freund Group. His vision and passion for innovation has left […]
The importance of spray drying, fluid beds and roll compaction in battery material processing
How three critical processes are shaping the future of energy storage. In an era dominated by the quest for sustainable energy solutions, the significance of battery technology cannot be overstated. […]
Current Processing Equipment Trends Podcast with ChargePoint Technology
Sustainability, customisation, and automation are key factors to remaining flexible in a continuously evolving pharma industry. Vice President of Global Business Development at Freund-Vector, Jamie Frizzell, joins Pharma Tech Talks […]
Another Satisfied Customer
Freund-Vector’s Technical Service Engineer for Brazil Renato Oliveira and Validation Engineer, Gavin Peterson successfully completed a 2 week trip for equipment validation at the Novamed site in Brazil. This machine […]
Process development scientists study the efficacy of using near-infrared spectroscopy for inline, real-time measurement of product moisture during two different wet granulation methods.
NIR spectroscopy provided significant advantages over offline moisture measurement in terms of time for sample analysis without a drop off in accuracy. In this study, repeatable moisture curves for a […]
Using Continuous Manufacturing (Wet Granulation) for Different Grades of Ceolus
Until now, batch manufacturing has been the main mode of pharmaceutical manufacture: raw materials are input and processed in a stage of the process then removed for input and process […]
Inaugural address from our new President
I am Greg Smith, and I am pleased to announce my appointment as President of FREUND-VECTOR CORPORATION (“FV”). Since 1997, when FV formed a partnership with FREUND CORPORATION, FV […]
PAT Processing Experts with a Process-Centric Approach
Process Analytical Technology (PAT) is a system for designing, analyzing, and controlling pharmaceutical manufacturing processes through measurements of critical quality and performance attributes of raw and processed materials to ensure […]
Leading the Way in Low Temperature Tablet Coating Processing
The DVA Chemical Company and Freund-Vector joined forces on a study to expose a new water dispersible pharmaceutical coating product able to be applied at tablet bed process temperatures lower […]
Freund-Vector Collaborates with Other Pharmaceutical Leaders on Roll Compaction Study (Part 2)
Use Of Different Mannitol Grades To Improve The Flow And Tableting Properties Of Powder Mixtures Dry Granulated By Roller Compaction The Freund-Vector European Laboratories co-authored an important study presented at […]
Cos.Mec Celebrates its 30th Anniversary
Freund-Vector wishes to congratulate Cos-Mec for their 30th Anniversary in business. As our sister company in the solid dosage equipment industry, we know together, we will strengthen our presence on […]
Freund-Vector’s Approach to Safely Processing Potent Compounds
The number of highly potent drugs in OSD (Oral Solid Dosage) production has risen sharply in recent years. As a result, containment is becoming ever more […]
Giuseppe Buratti: New Deputy Branch Manager, Freund-Vector’s European Laboratory
Along with my staff here at the Freund-Vector European Laboratory, we are happy to help address your processing requirements and provide on-site and online training. After working in the industry […]
Cos.Mec Acquisition
PRESS RELEASE FOR IMMEDIATE RELEASE: November 9, 2020 Notice of Acquisition of Cos.Mec of Italy On November 5, 2020, Freund Corporation, Tokyo Japan, acquired Cos.Mec S.r.l., a privately owned […]
High Shear Mixers | Is It Right For You?
The GRANUMEIST® (GMX) High Shear Granulator Mixer systems have been used for decades in the pharmaceutical industry. They are designed for efficient and homogeneous wet granulation of powders to form […]
VIRTUAL #F.A.T , ENSURING CONTINUITY FOR FREUND-VECTOR CUSTOMERS WORLDWIDE
As we endeavor to stem the spread of COVID-19, Freund-Vector has implemented a new service capability to ensure critical projects are not delayed. Freund-Vector has begun carrying out Factory Acceptance […]
Statement Concerning COVID-19
Dear valued clients, global partners and supporters: As we continue to monitor the latest information regarding the global COVID-19 outbreak, we are taking additional measures to ensure the safety of […]
Freund-Vector Leads Way in PAT Processing and Pellet Manufacturing
Detection of Moisture Using a NIR Filter Photometer on Dynamically Moving Particles in a Rotor Processor On November 4-5, 2019, Mitch Crawford, Associate Process Scientist, Freund-Vector presented a poster at […]
Freund-Vector Collaborates with Other Pharmaceutical Leaders on Roll Compaction Study (Part 1)
Evaluation of Different Mannitol Grades in Dry Granulation Process by Roller Compaction The Freund-Vector European Laboratories co-authored in an important study presented at the AAPS show November 4-5, 2019. Along […]
Freund-Vector has your CANNABIS Solutions!
Cannabis-infused products and medical marijuana are at the forefront of an innovative and promising industry. Fueled by a growing consumer base and enthusiasm, the race is on to develop effective, […]
Swap out your 1,000 L coating pan in less than 5 minutes!
VHC-Multi Pan Mounting Method Cedar Rapids, IA: August 29, 2019, The US Patent office announced a pending patent for a pan mounting method. This new design on the VHC-Multi allows for […]
PAT Monitoring of Coating Pan by NIR: PLS Method Calibration Approach
The 9th International Granulation Workshop took place in Lausanne, Switzerland on June 26-28, 2019. The granulation conference is the place to showcase the latest in agglomeration, granulation and particle technology […]
Mount Rushmore is more soluble than the next breakthrough drug!
Really? How can that be? After all, isn’t Mount Rush solid as a rock! True, but even rock dissolves when exposed to water. It will dissolve very, very, slowly over […]
From Powder to Pellet: How the GRANUREX® can help achieve your processing methods
Rotor Technology has been used to process multiparticulate pharmaceutical materials for many years, it’s an ideal situation for processing small particles. It provides excellent mixing, flowability with concurrent tangential spraying. […]
Freund-Vector 2 Bar Vented and 12 Bar Fluid Bed Containment Systems
With fluid bed systems, safety always must be considered as the highest priority. Due to static discharge, there always remains the risk of an explosive environment within the fluid bed […]
“Instantizing” Offers Solutions To Dispersing/Solubilizing Powders In Liquid
Think about when you put hot cocoa powder mix in a mug of hot water, how much of the powder floats on top of the surface? How quickly do you […]
Used Pharmaceutical Equipment: Things to Consider…
There are many types of used laboratory and process equipment are available on the secondary market. Most of what would be needed for a complete solid-dosage operation. Knowing the process […]
Joint Development with Ashland on Continuous Granulation
For the longest time, pharmaceuticals have been produced using a method known as “batch manufacturing,” which involves a multi-step, lengthy process that uses large-scale equipment. In recent years however manufacturing […]
Contained Tablet Coating Success Story – 1 µg/m3 Containment without an Isolator.
A customer contacted Freund-Vector asking for a requirement to coat tablets on a LDCS-Pro Hi Coater (150L batches) and needed contained loading, sampling and unloading of their tablets. The customer […]
Improving Particle Flow Characteristics Using Roll Compaction
On March 25-26, 2019, Freund-Vector through a joint partnership with Chemische Fabrik Budenheim KG, presented a poster at the 3rd European Pharma Congress in Bologna Italy on “Adjusting the Release […]
Wurster Spray PAT Monitoring by NIR: Calibration vs. PCA Trend Approach
Wurster Spray PAT Monitoring by NIR: Calibration vs. PCA Trend Approach The 3rd European Pharma Congress was held in Bologna Italy, March 25-26, 2019. The European Conferences on Pharmaceutics is […]
Another Coating Success Story – 5% Weight Gain @ 250 mL per Minute/Gun
The purpose of the experiment was to evaluate and compare the performances of different spray guns in various coating processes in a Freund-Vector VHC-5811 55 liter fully perforated coating pan. […]
Answers to Fluid Bed Processors Quiz
Last week Freund-Vector created a short quiz on Fluid Bed Processors on LinkedIn. The purpose of this quiz was to test customer’s knowledge on Freund-Vector’s Fluid Bed technology and processing […]
Freund Group Introduces Water Activity Meter
The Freund Group seeks to expand its non-pharmaceutical product business and take on new challenges that enable it to contribute to improving the quality of health and life of people […]
NIPTE – 2018 Research Conference Recap
The National Institute for Pharmaceutical Technology & Education (NIPTE) is a collaboration of academia, industry and other stakeholders using research, outreach and education to improve the way medicines are designed, […]
Pharmaceutical Technology Symposium – Sao Paulo, Brazil
The focus of this symposium was around Enabling Technologies and Innovation within the pharmaceutical industry. During this one-day event, there were presentations on a range of topics around formulation development, […]
Success Story – Tablet Coating @ 250 mL Per Minute/Gun
Last week, Freund-Vector conducted a pilot test to determine if tablets could be coated at 250 mL/minute/gun. After two days of testing on Freund-Vector’s VHC HI-COATER® 60 Coating System, the […]
The Value of Factory Acceptance Tests (FAT)
Are you the one who is responsible for installation and startup at your organization? Are you being told that there cannot be any issues or delays? Wouldn’t it be nice […]
Patent Issued – Process and Product Produced on Freund-Vector’s GXR
This week Freund-Vector and Grain Processing Corporation (GPC) received a patent related to microspheres using Freund-Vector’s Granurex (GXR), the most powerful pellet/powder processor available in the market place. Microspheres composed […]
Basic Batch Coater Operating Parameters and Setup
In the April edition of Tablets and Capsules, Mr. Nick Slater, Freund-Vector’s Senior Process Development Scientist, discusses the qualitative relationships between key parameters when using a perforated pan film coater. […]
Freund-Vector’s Perforated Coating Pans
Starting with the development of the world’s first successful automated film coating machine in 1964, the Freund group has established itself as a global leader in tablet coating systems and […]
High-Shear Granulation Processes: Comparison of Different Methods of Binder Addition on Particle Size and Shape
Freund-Vector’s Process Scientists conducted a study to determine what happens to particle size and shape when different binder activations are used with high-shear granulation processes. This study was done with […]
Creating Enteric Coated Omeprazole Pellets on a Conical Rotor
Is there a solution that could take an existing Wurster process and transfer it to a conical rotor to reduce the processing time and pieces of equipment required to complete […]
Utilization of Starch Micro-Spheres-Facilitate High API Loading in Particles Below 250 Microns
Active Pharmaceutical Ingredients (API) layering onto multi-particulate core materials has become an increasingly popular method of drug delivery in the pharmaceutical industry in recent years. The ability to control dosing, […]
Continuous Manufacturing: Alternative to Batch Processing
Most solid dosage drugs are manufactured using “batch” technology, a process where the finished product has been made after many stops and starts in a series of steps. In comparison, […]
Taste Masking Multi-Particulates Utilizing Dry Polymer Layering
Taste masking of multi-particulate dosage forms has become widespread in the pharmaceutical industry, particularly with small particles used in orally disintegrating tablets (ODT) applications. The amount of coating required to […]
An Evaluation of a One-Step vs. Multi-Step Milling Process for Roller Compacted Ribbon
Roller compaction is a dry granulation process used in the pharmaceutical industry to create granules for manufacturing solid dosage forms such as tablets and capsules. During the roller compaction operation, […]
How The AT Spray Gun Improves Film Coating Processes
During the past 20 years there have been substantial improvements in the variety and quality of tablet coating materials (i.e. ease of preparation, aqueous controlled release, reduced viscosity/higher solids, etc.). […]
Comparison of Wurster and Dry Powder Layering Processes- Controlled Release Coatings of Ethylcellulose on Drug Loaded Multiparticulates
Freund-Vector and Dow Chemical conducted a study of spray coatings of ethylecllulose for controlled release on multi-particulate dosage forms. Long process times, need for organic solvent capabilities and particulate agglomeration […]
Comparison of Wurster processor with a GRANUREX® (GXR) rotor processor: 100-300 micron Omeprazole coated beads
The purpose of this research was to compare two processes, an established Wurster coating process and a GRANUREX® process for producing 100-300 micron Omeprazole coated beads to determine if advantages […]